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Reduction of suppressor cells in cancer patients treated with OK-432

โœ Scribed by A. Uchida; T. Hoshino

Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
73 KB
Volume
2
Category
Article
ISSN
0192-0561

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Reduction of suppressor cells in cancer
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## Abstract Okโ€432, a streptococcal preparation, was intradermally injected daily into patients with advanced cancer of the stomach or lung for 4 weeks and the effects of OKโ€432 on the mitogenic responses of cancer patients were followed. The cells involved in the depression of the response of untr

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Intrapleural administration of OK432 in cancer patients: Activation of nk cells and reduction of suppressor cells
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## Abstract Twelve patients with carcinomatous pleural effusions were treated with single intrapleural (i.pl.) administration of OK432 on day 0 and the effects of i.pl. OK432 on natural killer (NK) cell activity were followed on day 7. Two patients showed no clinical evidence of therapeutic benefit