Reduction of substituted spiro[cyclopropane-3-(1-pyrazolines)] to spiro[cyclopropane-3-pyrazolidines] and 1-(2-aminoethyl)cyclopropylamine derivatives
β Scribed by I. V. Kostyuchenko; E. V. Shulishov; V. A. Korolev; V. A. Dokichev; Yu. V. Tomilov
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 483 KB
- Volume
- 54
- Category
- Article
- ISSN
- 1573-9171
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## Abstract magnified image A series of new spiro[cyclopropaneβ1,4β²βpyrazolβ3βone] derivatives **3aβh** were synthesized by the reaction of 4βarylideneβ3__H__βpyrazolβ3βone **1** with secondary and tertiary carbanions derived from a methylene and methine group bearing both a leaving group and elec
A one-step synthesis of ethyl 2,3-dihydronaphtho[1,2-b]furan-2-carboxylate and/or ethyl 4'-oxospiro[cyclopropane-1,1'(4'H)-naphthalene]-2'-carboxylate derivatives 2 and 3, respectively, from substituted naphthalen-1-ols and ethyl 2,3-dibromopropanoate is described (Scheme 1). Compounds 2 were easily