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Reduction of substituted spiro[cyclopropane-3-(1-pyrazolines)] to spiro[cyclopropane-3-pyrazolidines] and 1-(2-aminoethyl)cyclopropylamine derivatives

✍ Scribed by I. V. Kostyuchenko; E. V. Shulishov; V. A. Korolev; V. A. Dokichev; Yu. V. Tomilov


Publisher
Springer
Year
2005
Tongue
English
Weight
483 KB
Volume
54
Category
Article
ISSN
1573-9171

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A one-step synthesis of ethyl 2,3-dihydronaphtho[1,2-b]furan-2-carboxylate and/or ethyl 4'-oxospiro[cyclopropane-1,1'(4'H)-naphthalene]-2'-carboxylate derivatives 2 and 3, respectively, from substituted naphthalen-1-ols and ethyl 2,3-dibromopropanoate is described (Scheme 1). Compounds 2 were easily