Reduction of radiation damage and other benefits of short wavelengths for macromolecular crystallography data collection

Reduction of X-ray-induced radiation dam

Reduction of X-ray-induced radiation damage of macromolecular crystals by data collection at 15 K: a systematic study

✍ Meents, A. ;Wagner, A. ;Schneider, R. ;Pradervand, C. ;Pohl, E. ;Schulze-Briese, 📂 Article 📅 2007 🏛 International Union of Crystallography 🌐 English ⚖ 658 KB

The cryocooling of protein crystals to temperatures of around 100 K drastically reduces X-ray-induced radiation damage. The majority of macromolecular data collection is therefore performed at 100 K, yielding diffraction data of higher resolution and allowing structure determination from much smalle