Reduction of ketones with polydibenzo-18-crown-6-borohydride
β Scribed by A. Sarkar; Br Rao
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 251 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Misinterpretations regarding the selectivity of tetraalkylammonium borohydride reductions in dichloromethane are resolved. Tetrabutylamnonium borohydride offers several advantages, but both it and tetraethylammonium borohydride are highly useful synthetic reagents.
In the course of an investigation of solvent effects on the relative reactivities of ketones with borohydridel, we have observed some unusual features of reductions in pyridine solvent which are relevant to recent discussions of the mechanism and stereochemistry of metal hydride reductions2,3,4,5 an
## Abstract The rates for the reduction of ketones with sodium borohydride are interpreted in terms of two parameters, both derived from forceβfield calculations; __i.e.__ the strain difference between alcohol and ketone (Ξ strain) and the steric hindrance towards approach of the hydride R. Models