The photochemical synthesis of indole derivatives starting from the indoline-2-thiones 1 is described. Irradiation of indoline-2-thiones 1 in the presence of alkenes 3 gave 2-alkyl-3H-indoles 4-7 or 2-alkylindoles 8-22 through the ring cleavage of the intermediates, spirocyclic amino-thietanes, init
Reduction of Indolin-2-ones and Desulfurization of Indoline-2-thiones to Indoline and Indole Derivatives
✍ Scribed by Takehiko Nishio; Norikazu Okuda; Choji Kashima
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- German
- Weight
- 312 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
1 9. VI. 90
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## Abstract The antioxidant behavior of a series of new synthesized substituted indoline‐2‐ones and indolin‐2‐thiones was investigated in this study using an oxygen radical absorbance capacity assay (ORAC$\_{ROO\mathop{\bullet}^{\!\!\!\!-}}$) and 2,2′‐azobis(2‐amidino‐propane) dihydrochloride (AAPH
## Abstract Indoline‐2‐thiones **1a‐b,d,f,h**, which have at least one hydrogen at the 3‐position reacted with α‐halo ester **2a‐d**, α‐halo ketones **2e‐f**, and a‐bromoacetonitrile **2g** to give 2‐alkylthioindole derivatives **3–11**. In a similar manner treatment of 3,3‐disubstituted indoline‐2