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Reduction of glutamate release and protection against ischemic brain damage by BW 1003C87

✍ Scribed by B.S. Meldrum; J.H. Swan; M.J. Leach; M.H. Millan; R. Gwinn; K. Kadota; S.H. Graham; J. Chen; R.P. Simon


Book ID
115803231
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
755 KB
Volume
593
Category
Article
ISSN
0006-8993

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Protection against ischemic brain damage
✍ Feng Li; Nobuhiko Omori; Takeshi Hayashi; Guang Jin; Keiko Sato; Isao Nagano; Mi πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 231 KB

## Abstract To determine the effect of immunophilin ligand GPI‐1046 on ischemic brain injury, 90 min of transient middle cerebral artery occlusion (MCAO) was carried out in rat brains. In contrast to cases treated with vehicle, the infarct volume was reduced greatly and rotamase activity was inhibi