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Reduction of femoral artery bleeding post catheterization using a collagen enhanced fibrin sealant

✍ Scribed by Falstrom, Jeanne K. ;Goodman, Norman C. ;Ates, Gursel ;Abbott, Robert D. ;Powers, Eric R. ;Spotnitz, William D.

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 43 KB
Volume: 41
Category: Article
ISSN: 0098-6569
DOI: 10.1002/(sici)1097-0304(199705)41:1<79::aid-ccd18>3.0.co;2-l

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✦ Synopsis

As the number of cardiac catheterization procedures increases, so do associated complications and costs. This study suggests that the application of a new collagen enhanced fibrin sealant, Collaseal, may be used effectively to achieve rapid hemostasis at the arterial puncture site following femoral artery catheterization. Results in nine dogs anticoagulated with heparin (activated clotting time 396 +/- 107, mean +/- S.D.) revealed a statistically significant reduction in signs of gross bleeding in the sealant-treated groins as compared to control (2 versus 9, P = .0156). These results indicate that this commercially produced sealant might be used in human patients undergoing cardiac catheterization to decrease complications, lengths of stay, and costs.

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Reduction of femoral arterial bleeding post catheterization using percutaneous application of fibrin sealant

✍ Ismail, Suad ;Combs, Matthew J. ;Goodman, Norman C. ;Teotia, Sumeet S. ;Teates, 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 839 KB

The number of cardiac catheterizations performed yearly is growing with correspondingly increasing amounts of morbidity, complications, and hospital costs. This study suggests that fibrin sealant instillation via an arterial sheath at the completion of femoral catheterization may improve hemostasis.