✦ LIBER ✦
Reduction of extracellular superoxide dismutase activity by decapeptide derived from FGF-receptor
✍ Scribed by Jean Willems; Wim Noppe; Herman Slegers
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 152 KB
- Volume
- 19
- Category
- Article
- ISSN
- 1065-6995
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Several synthetic decapeptides containing an HAV tripeptide motif were tested for their ability to modulate the enzymatic activity of rat extracellular SOD, an enzyme which also contains an HAV motif. Out of nine decapeptides that were tested, only a FGF‐receptor derived peptide was active as a negative modulator of enzyme activity. These results strenghten the thesis that HAV motifs are not only involved in homophilic interactions and suggest that soluble FGF‐receptor molecules might moderate the activity of extracellular SOD.