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Reduction of dorsolateral prefrontal cortex gray matter in late-life depression

โœ Scribed by Cheng-Chen Chang; Shun-Chieh Yu; Douglas R. McQuoid; Denise F. Messer; Warren D. Taylor; Kulpreet Singh; Brian D. Boyd; K. Ranga R. Krishnan; James R. MacFall; David C. Steffens; Martha E. Payne

Book ID
113866549
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
349 KB
Volume
193
Category
Article
ISSN
0925-4927

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## Background: Signal hyperintensities on magnetic resonance imaging in late-life depression are associated with treatment resistance and poor outcome. these lesions are probably vascular in origin and proposed sites for vascular damage include the dorsolateral prefrontal cortex (dlpfc) and anterio