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Reduction of Cisplatin-Induced Emesis by a Selective Neurokinin-1–Receptor Antagonist

✍ Scribed by Navari, Rudolph M.; Reinhardt, Rick R.; Gralla, Richard J.; Kris, Mark G.; Hesketh, Paul J.; Khojasteh, Ali; Kindler, Hedy; Grote, Thomas H.; Pendergrass, Kelly; Grunberg, Steven M.; Carides, Alexandra D.; Gertz, Barry J.


Book ID
120055844
Publisher
Massachusetts Medical Society
Year
1999
Tongue
English
Weight
105 KB
Volume
340
Category
Article
ISSN
0096-6762

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✍ Simon Van Belle; Michael R. Lichinitser; Rudolph M. Navari; August M. Garin; Mar 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 109 KB 👁 1 views

## Abstract ## BACKGROUND Recent studies have suggested that antiemetic therapy with a triple combination of the neurokinin‐1 receptor antagonist MK‐869, a serotonin (5‐HT~3~) antagonist, and dexamethasone provides enhanced control of cisplatin‐induced emesis compared with standard therapy regimen