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Reduction of adipose tissue lipoprotein lipase activity as a result of in vivo administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin to the guinea pig

โœ Scribed by David W. Brewster; Fumio Matsumura

Book ID
115780574
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
736 KB
Volume
37
Category
Article
ISSN
0006-2952

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To study the long-term effect of 2,3,7,8tetrachlorodibenzo-p-dioxin (TCDD) on the DNAbinding activity of nuclear transcription factors; a single dose of TCDD was injected intraperitoneally to male guinea pigs (1 lg/kg i.p.). The animals were killed after 1, 2, 10, 20, 28, and 40 days, and DNA-bindin