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Reduction of adhesion formation by postoperative administration of ionically cross-linked hyaluronic acid

✍ Scribed by Douglas B. Johns; Kathleen E. Rodgers; William D. Donahue; Timothy C. Kiorpes; Gere S. diZerega


Book ID
119421998
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
647 KB
Volume
68
Category
Article
ISSN
1556-5653

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Post-operative peritoneal adhesions can cause pelvic pain, infertility, and potentially lethal bowel obstruction. We have designed and synthesized injectable hydrogels that are formed by mixing hydrazide-modified hyaluronic acid (HA) with aldehyde-modified versions of cellulose derivatives such as c