Reduction of adhesion formation by intraperitoneal administration of arg-gly-asp-containing peptides
β Scribed by Kathleen E Rodgers; Wefki Girgis; Joseph Campeau; Gere S diZerega
- Book ID
- 119423013
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 836 KB
- Volume
- 70
- Category
- Article
- ISSN
- 1556-5653
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## Abstract A photoreactive octapeptide (GlyβGlyβGlyβArgβGlyβAspβSerβPro), into which the cell adhesive tripeptidyl sequence ArgβGlyβAsp (RGD) was incorporated, was derivatized with 4βazidobenzoyloxysuccinimide at its __N__βterminal. Photochemical surface immobilization of the RGD peptide on poly (
We report on the inhibition of wound implantation by TA3Ha mammary carcinoma cells by Arg-Gly-Asp containing proteins and peptides using a hepatic wedge resection model. Intravenously injected TA3Ha cells rarely form tumor in the liver of syngeneic mice, but after hepatic wedge resection, 45% (107/2