Reduction of Acetylenic Compounds to (E)-Olefins by Alkali Metals – An Investigation of the Scope

✍ Scribed by Lambert Brandsma; Willem F. Nieuwenhuizen; Jan W. Zwikker; Uno Mäeorg

• Publisher: John Wiley and Sons
• Year: 1999
• Tongue: English
• Weight: 203 KB
• Volume: 1999
• Category: Article
• ISSN: 1434-193X
• DOI: 10.1002/(sici)1099-0690(199904)1999:4<775::aid-ejoc775>3.0.co;2-3

✦ Synopsis

Efficient procedures have been developed for the two or more (isolated) triple bonds are reduced considerably more easily than are monoynes. stereospecific reduction by alkali metals of disubstituted acetylenes with long carbon chains. Acetylenes containing fate was used to neutralize the tBuOLi formed during the during the reduction. This alcohol was preferred to meth- [a] Department of Preparative Organic Chemistry, anol or ethanol because of its much slower reaction with