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Reduction in the frequency of N-methyl-N-nitrosourea-induced somatic mutations in Tradescantia by pretreatment with low doses of alkylating agents

✍ Scribed by Jiří Velemínský; Tomáš Gichner; Jan Šatava


Book ID
113254370
Publisher
Elsevier Science
Year
1983
Weight
285 KB
Volume
122
Category
Article
ISSN
0165-7992

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The mutagenic interaction between N-ethyl-N-nitrosourea (ENU) and X-rays was tested in the stamen hairs of Tradescantia clone BNL 4430, a blue/pink heterozygote. ENU, a monofunctional alkylating agent with a low Swain-Scott substrate constant (s) of 0.26, exhibited a strong cytotoxicity. ENU-induced