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Reduction-degradable brushed polyethylenimine derivative synthesized by click chemistry for gene delivery

✍ Scribed by Zhang, Guangyan; Jiang, Xulin; Liu, Jia; Yang, Qizhi; Zhuo, Renxi


Book ID
122319223
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
234 KB
Volume
172
Category
Article
ISSN
0168-3659

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## Abstract Reducible disulfide‐containing hyperbranched PEI‐SS‐HP was synthesized via click chemistry and evaluated as nonviral gene carrier. The structure of the polymers was confirmed by ^1^H NMR and FTIR. It was shown that the PEI‐SS‐HP was able to bind plasmid DNA to positively charged nanopar