Approximately 40ยฑ60% of all amputations of the lower extremity are performed in patients with diabetes. More than 85% of these amputations are precipitated by a foot ulcer deteriorating to deep infection or gangrene. The prevalence of diabetic foot ulcers has been estimated to be 3ยฑ8%. The complexit
Reducing the incidence of foot ulceration and amputation in diabetes
โ Scribed by Cynthia L. Bartus; David J. Margolis
- Book ID
- 107536101
- Publisher
- Current Science Inc.
- Year
- 2004
- Tongue
- English
- Weight
- 298 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1534-4827
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Peripheral neuropathy is one of the most common long-term complications of Type 2 diabetes. A population-based study in the north of England showed that 42 % of Type 2 diabetic patients had clinical evidence of neuropathy. The Diabetes Control and Complications Trial (DCCT) has shown that the incide
## Abstract The use of tissue engineered human donor skin replacement therapy in a longstanding plantar ulceration in a patient with diabetes mellitus is described. The ulceration healed in 14 weeks, having been present for 10 years.
## Abstract ## Background Chronic foot ulceration is a major source of morbidity in diabetic patients. Despite traditional comprehensive wound management, including vascular reconstruction, there remains a cohort of patients with non-responding wounds, often resulting in amputation. These wounds m