Reducing Mortality in the Perioperative Period

✍ Scribed by Giovanni Landoni, Laura Ruggeri, Alberto Zangrillo (eds.)

• Publisher: Springer International Publishing
• Year: 2017
• Tongue: English
• Leaves: 156
• Edition: 2
• Category: Library

✦ Synopsis

This second edition presents the first update on a consensus process during which all evidence from the literature with a survival benefit in the perioperative period was gathered, and in which 500 physicians from 61 countries worked to confirm the findings.

Perioperative morbidity and mortality currently represent a public health problem, as mortality alone is 1-4% in Western countries. Surprisingly, randomized evidence of survival benefit in the perioperative period is available for only 12 topics, while two drugs have been demonstrated to increase mortality. This book offers a complete description of each topic with updated evidence from the literature. Each chapter deals with a specific drug or technique and is structured into the following: background knowledge, main evidence from the literature, and a practical how-to section. Lastly, the book describes in detail the consensus process used, which served to reinforce the systematic review and which is currently being used and improved in other settings with growing success.

Written by respected international experts, Reducing Mortality in the Perioperative Period, 2^nd ed. will be of interest to a wide variety of specialists, including anesthesiologists, intensivists, surgeons and cardiologists.

✦ Table of Contents

Front Matter....Pages i-vi
The Risks and Benefits of the Consensus Process....Pages 1-7
The Process of Consensus Building....Pages 9-14
Noninvasive Ventilation and Perioperative Mortality....Pages 15-22
Role of Inhalational Anesthetic Agents in Reducing Perioperative Mortality....Pages 23-27
Can Neuraxial Anesthesia Reduce Perioperative Mortality?....Pages 29-34
Role of Hemodynamic Optimization in Reducing Perioperative Mortality....Pages 35-46
Levosimendan....Pages 47-54
Perioperative β-Blocker Therapy....Pages 55-62
Leukocyte Depletion of Transfused Blood May Reduce Mortality in Cardiac Surgery Patients....Pages 63-71
Reducing Perioperative Mortality with the Intra-Aortic Balloon Pump....Pages 73-77
Selective Decontamination of the Digestive Tract....Pages 79-86
Role of Insulin in Reducing Mortality in the Perioperative Period....Pages 87-95
Aprotinin: Pharmacological Benefits and Safety....Pages 97-103
Liberal Transfusion Strategy in the Perioperative Period....Pages 105-111
Reducing Mortality in the Perioperative Period: Remote Ischemic Preconditioning....Pages 113-120
Statins and Perioperative Mortality....Pages 121-129
Tranexamic Acid to Reduce Perioperative Mortality....Pages 131-136
Reducing Mortality in the Perioperative Period: A Continuous Update....Pages 137-146
Randomized Evidence of Mortality Reduction Not Confirmed in Most Recent Works: A Methodological Problem....Pages 147-152
Back Matter....Pages 153-158

✦ Subjects

Anesthesiology;Surgery;Intensive / Critical Care Medicine;Internal Medicine