Reduced Tyrosine Kinase Specific Activity is Associated with Hypophosphorylation of pp60c-srcin Cells Infected with Avian Erythroblastosis Virus

Stimulation of pp60c-src tyrosyl kinase

Stimulation of pp60c-src tyrosyl kinase activity in polyoma virus–infected mouse cells is closely associated with polyoma middle tumor antigen synthesis

✍ Joseph B. Bolen; Andrew M. Lewis Jr; Mark A. Israel 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 732 KB

We have examined the effect of polyoma virus infection of primary mouse embryo cells on the tyrosyl kinase activity associated with the cellular src gene product, pp60c-src. The results of our studies demonstrate that infection of mouse cells with wild-type polyoma virus or viral mutants capable of