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Reduced susceptibility to azoxymethane-induced aberrant crypt foci formation and colon cancer in growth hormone deficient rats

✍ Scribed by Robert E. Carroll; Robert A. Goodlad; Aleksandra J. Poole; Angela L. Tyner; R. Brooks Robey; Steven M. Swanson; Terry G. Unterman

Book ID: 116512296
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 536 KB
Volume: 19
Category: Article
ISSN: 1096-6374
DOI: 10.1016/j.ghir.2009.02.001

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## Abstract __S__‐Adenosyl L‐methionine (SAM) is a universal methyl group donor to various intermediary metabolites, hormones, proteins, neurotransmitters, phospholipids and nucleic acids. Deficiency of folate, which plays a role in the synthesis of SAM leads to increased risk for colon cancer. Thi