Reduced satiating effect of d-fenfluramine in serotonin 5-HT2C receptor mutant mice
โ Scribed by Steven P. Vickers; Peter G. Clifton; Colin T. Dourish; Laurence H. Tecott
- Book ID
- 105884924
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 227 KB
- Volume
- 143
- Category
- Article
- ISSN
- 0033-3158
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Previously it has been shown that excitatory effects of 5-hydroxytryptamine (5-HT) upon interneurons in the rat piriform cortex are mediated by 5-HTzA receptors. This receptor is linked to phosphoinositide turnover, and one consequence of stimulating this receptor is the activation of protein kinase
Several studies have suggested a close interaction between serotonin (5-HT) and BDNF; however, little is known of the specific relationship between BDNF and the 5-HT 2C receptor. Therefore, in this study we investigated BDNF expression in 5-HT 2C receptor knockout mice (5-HT 2C KO). We also assessed