Reduced Regional Integration in the Default Network of Patients with Very Mild Alzheimer's Disease Detected by Bootstrapping Rest-fMRI Data

Recovery of hippocampal network connecti

Recovery of hippocampal network connectivity correlates with cognitive improvement in mild alzheimer's disease patients treated with donepezil assessed by resting-state fMRI

✍ Joseph S. Goveas; Chunming Xie; B. Douglas Ward; Zhilin Wu; Wenjun Li; Malgorzat 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 449 KB

## Abstract ## Purpose: To identify the neural correlates of cognitive improvement in mild Alzheimer's disease (AD) subjects following 12 weeks of donepezil treatment. ## Materials and Methods: Resting‐state functional connectivity magnetic resonance imaging (R‐fMRI) was used to measure the hipp