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Reduced Prevalence of Smokers in Sarcoidosis : Results of a Case-Control Study

✍ Scribed by R. A. HARF; C. ETHEVENAUX; J. GLEIZE; M. PERRIN-FAYOLLE; J. C. GUERIN; C. OLLAGNIER


Book ID
118723301
Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
402 KB
Volume
465
Category
Article
ISSN
0890-6564

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## Abstract Poly(ADP‐ribose) polymerase (PARP), a nuclear enzyme that is catalytically activated by DNA strand breaks, plays a complex role in DNA repair. Using NAD^+^ as a precursor, it catalyzes the formation of ADP‐ribose polymers, which are attached to various proteins. Defects in DNA repair pa