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Reduced muscarinic receptor plasticity in frontal cortex of aged rats after chronic administration of cholinergic drugs

✍ Scribed by Norman W. Pedigo Jr.; Darrel M. Polk


Book ID
118340884
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
481 KB
Volume
37
Category
Article
ISSN
0024-3205

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Pharmacological adaptations and muscarin
✍ Norman W. Pedigo πŸ“‚ Article πŸ“… 1988 πŸ› Springer 🌐 English βš– 573 KB

Receptor plasticity is an important compensatory process by which the central nervous system adapts to pathological insult or long-term exposure to drugs. Senescent animals may show an age-related impairment of muscarinic receptor up- or down-regulation after chronic exposure to cholinergic drugs. T