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Reduced Mitochondrial l-Arginine Transport Contributes to the Pathogenesis of Heart Failure

โœ Scribed by K. Venardos; D. Williams; Z. Yang; M. Byrne; D. Kaye


Book ID
116527016
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
63 KB
Volume
19
Category
Article
ISSN
1443-9506

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Reduced L-arginine transport contributes
โœ Kylie M. Venardos; Amanda J. Zatta; Tanneale Marshall; Rebecca Ritchie; David M. ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 232 KB

## Abstract Myocardial injury due to ischemiaโ€reperfusion (Iโ€R) damage remains a major clinical challenge. Its pathogenesis is complex including endothelial dysfunction and heightened oxidative stress although the key driving mechanism remains uncertain. In this study we tested the hypothesis that