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Reduced kappa-opioid activity in a rat model of cholestasis

โœ Scribed by Saadet Inan; Alan Cowan


Book ID
113585521
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
108 KB
Volume
518
Category
Article
ISSN
0014-2999

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## Abstract Excessive glutamate transmission in the basal ganglia is a major factor in the neural mechanisms underlying parkinsonian akinesia. Activation of K opioid receptors causes a presynaptic reduction in glutamate release. K opioid receptors are concentrated in those regions of the basal gang