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Reduced insulin-induced phosphatidylinositol-3-kinase activation in peripheral blood mononuclear leucocytes from patients with Alzheimer's disease

✍ Scribed by Paola Castri; Luisa Iacovelli; Antonio De Blasi; Franco Giubilei; Arianna Moretti; Francesca Tari Capone; Ferdinando Nicoletti; Francesco Orzi


Book ID
109026181
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
209 KB
Volume
26
Category
Article
ISSN
0953-816X

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## Abstract Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system, and it is considered to be a T helper 1 (Th1) cell‐mediated autoimmune disease. T‐bet has been identified as a key transcription factor for the development of Th1 cells and the inducti