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Reduced human mismatch repair protein expression in the development of precancerous skin lesions to squamous cell carcinoma

✍ Scribed by Sheng-Ben Liang,Mutsuo Furihata,Tamotsu Takeuchi,Hiroshi Sonobe…


Book ID
113042411
Publisher
Springer
Year
2001
Tongue
English
Weight
141 KB
Volume
439
Category
Article
ISSN
1432-2307

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Human mismatch repair gene (hMSH2) produ
✍ Tie-Xiong Jin; Mutsuo Furihata; Ichiro Yamasaki; Masayuki Kamada; Sheng-Ben Lian 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 288 KB 👁 2 views

## Background: Several convincing studies have shown that the hmsh2 gene plays major roles in mismatch repair by recognizing mismatched bases and preventing mutations during dna replication. loss of this function may result in the accumulation of dna replication errors or even the mutator phenotype