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Reduced hippocampal CA1 Ca2+-induced long-term potentiation is associated with age-dependent impairment of spatial learning

✍ Scribed by Giovanni Diana; Maria Rosaria Domenici; Arsenia Scotti de Carolis; Alberto Loizzo; Stefano Sagratella


Book ID
113127548
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
379 KB
Volume
686
Category
Article
ISSN
0006-8993

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The effect of two types of electrical stimulation designed to induce long-lasting plasticity of the Schafferkommissural inputs to CA1 pyramidal neurons was investigated using in vitro hippocampal slices made from young (3-6 month) and old (24-27 month) Fischer 344 rats. The first stimulation paradig