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Reduced Haloperidol/Haloperidol ratio and clinical outcome in schizophrenia: Preliminary evidences

✍ Scribed by Altamura, Carlo; Mauri, Massimo; Cavallaro, Roberto; Colacurcio, Fulgenzio; Gorni, Alfredo; Bareggi, Silvio

Book ID: 121749934
Publisher: Elsevier Science
Year: 1988
Tongue: English
Weight: 326 KB
Volume: 12
Category: Article
ISSN: 0278-5846
DOI: 10.1016/0278-5846(88)90013-9

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## Abstract Fifteen chinese schizophrenic patients were given titrated doses of haloperidol (0.05‐0.42 mg/kg) for two weeks. All these 15 patients were in clinical remission on maintenance dose of haloperidol. The mean plasma haloperidol and reduced haloperidol concentrations were 16.8 ± 4.8 ng/ml