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Reduced Granulocyte-Macrophage Colony-Stimulating Activity by Mitogen-Stimulated Lymphocytes from Patients with Aplastic Anaemia

✍ Scribed by Thomas L. Weatherly; Thomas A. Fleisher; Douglas M. Strong


Book ID
114709078
Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
377 KB
Volume
43
Category
Article
ISSN
0007-1048

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The hematopoietic system in patients with aplastic anemia (AA) shows both quantitative and qualitative deficiencies, i.e., reduced numbers of hematopoietic progenitor cells (HPC) and impaired HPC proliferation in long-term marrow cultures (LTMC). Since recombinant human granulocyte macrophage-colony