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Reduced glutathione levels and expression of the enzymes of glutathione synthesis in cryopreserved hepatocyte monolayer cultures

✍ Scribed by David J. Stevenson; Caroline Morgan; Lesley I. McLellan; M. Helen Grant


Book ID
116919558
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
359 KB
Volume
21
Category
Article
ISSN
0887-2333

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Many of the differentiated functions of hepatocytes are lost in culture, yet addition of certain medium supplements can aid in the retention of differentiated character. Therefore, the effect of time in monolayer culture on rat hepatocyte glutathione (GSH) synthesis and sensitivity to the GSH detoxi