DNA cytosine methylation in brain of pat
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Netanel G. Schwob; Josephine Nalbantoglu; Kenneth E. M. Hastings; Tom Mikkelsen;
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Article
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1990
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John Wiley and Sons
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English
โ 399 KB
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## Abstract We developed a novel quantitative assay to test the hypothesis that defects in DNA cytosine methylation might be responsible for the brain chromatin abnormalities and transcriptional alterations observed in patients with Alzheimer's disease (AD). We found no significant difference in pe