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Reduced gluconeogenesis and lactate clearance in Huntington's disease

✍ Scribed by Knud Josefsen; Signe M.B. Nielsen; André Campos; Thomas Seifert; Lis Hasholt; Jørgen E. Nielsen; Anne Nørremølle; Niels H. Skotte; Niels H. Secher; Bjørn Quistorff


Book ID
113812522
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
507 KB
Volume
40
Category
Article
ISSN
0969-9961

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Mitochondrial defects that affect cellular energy metabolism have long been implicated in the etiology of Huntington's disease (HD). Indeed, several studies have found defects in the mitochondrial functions of the central nervous system and peripheral tissues of HD patients. In this study, we invest