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Reduced fertility of female mice lacking CD81

✍ Scribed by Eric Rubinstein; Ahmed Ziyyat; Michel Prenant; Edyta Wrobel; Jean-Philippe Wolf; Shoshana Levy; François Le Naour; Claude Boucheix

Book ID
116975464
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
255 KB
Volume
290
Category
Article
ISSN
0012-1606

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✍ Le Naour, F. 📂 Article 📅 2000 🏛 American Association for the Advancement of Scienc 🌐 English ⚖ 603 KB

CD9 is a widely expressed cell surface molecule that belongs to the tetraspanin superfamily of proteins. The tetraspanins CD9, KAI-1/CD82, and CD63 are involved in metastasis suppression, an effect that may be related to their association with β1 integrins. Knockout mice lacking CD9 were created to