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Reduced expression of the Sp4 gene in mice causes deficits in sensorimotor gating and memory associated with hippocampal vacuolization

✍ Scribed by Zhou, X; Long, J M; Geyer, M A; Masliah, E; Kelsoe, J R; Wynshaw-Boris, A; Chien, K R


Book ID
110059905
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
697 KB
Volume
10
Category
Article
ISSN
1359-4184

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## Abstract Mutations of the __ATRX__ gene, which encodes an ATP‐dependent chromatin‐remodeling factor, were identified in patients with α‐thalassemia X‐linked mental retardation (ATR‐X) syndrome. There is a milder variant of ATR‐X syndrome caused by mutations in the Exon 2 of the gene. To examine