Reduced expression of p27Kip1 protein is associated with poor clinical outcome of breast cancer patients treated with systemic chemotherapy and is linked to cell proliferation and differentiation

Expression of p27Kip1 and cyclin D1 prot

Expression of p27Kip1 and cyclin D1 proteins is inversely correlated and is associated with poor clinical outcome in human gastric cancer

✍ Han, Sehwan; Kim, Hong-Yong; Park, Kyeongmee; Lee, Myung-Soo; Kim, Hong-Joo; Kim 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 318 KB 👁 2 views

Background and Objectives: p27Kip1 is an inhibitor of cyclindependent kinases and is speculated to be a potential prognostic indicator in numerous human cancers. We investigated expression of p27Kip1 along with cyclin D1 in gastric cancer to estimate the clinical utility of p27Kip1. Methods: Immunoh