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Reduced expression of NLRP3 and MEFV in human ischemic heart tissue

✍ Scribed by Hermansson, Cecilia; Lundqvist, Annika; Wasslavik, Carina; Palmqvist, Lars; Jeppsson, Anders; Hultén, Lillemor Mattsson

Book ID
122931694
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
531 KB
Volume
430
Category
Article
ISSN
0006-291X

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## Abstract Calcineurin (CaN) has been reported as a critical mediator for cardiac hypertrophy and cardiac myocyte apoptosis. In the present study, we investigated the activity and expression of CaN and the effect of calpain in rat heart after ischemia and reperfusion. Rat ischemic heart showed sig