Reduced expression of C/EBPα protein in hepatocellular carcinoma is associated with advanced tumor stage and shortened patient survival

Decreased expression of p27 protein is a

Decreased expression of p27 protein is associated with advanced tumor stage in hepatocellular carcinoma

✍ Andrea Tannapfel; Dorothee Grund; Alexander Katalinic; Dirk Uhlmann; Ferdinand K 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 217 KB 👁 2 views

Reduced expression of the cyclin-dependent kinase inhibitor p27 has previously been correlated with fatal clinical outcome in some tumors, including gastric, breast, and prostate cancers. For hepatocellular carcinoma, the findings are equivocal. In situ hybridization and immunohistochemistry were pe