Reduced expression of CD47 during murine
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Sanjay Khandelwal; Nico Van Rooijen; Rajiv K. Saxena
📂
Article
📅
2007
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Elsevier Science
🌐
English
⚖ 276 KB
**BACKGROUND:** Almost 2 percent of murine blood red blood cells (RBCs) are destroyed each day and are replaced by fresh RBCs generated through the process of erythropoiesis. RBCs to be destroyed are phagocytosed by macrophages in the reticuloendothelial system, especially in the spleen. CD47 molecu