The enzyme O 6 -methylguanine-DNA methyltransferase (MGMT) protects cells from the cytotoxic and mutagenic effects of alkylating agents. Approximately 20% of tumor cell lines lack MGMT activity and are highly sensitive to alkylating agents. In established cancer cell lines, MGMT expression appears t
Reduced expression and increased CpG dinucleotide methylation of the rat APOBEC-1 promoter in transgenic rabbits
β Scribed by Frank Apostel; Reinhard Dammann; Gerd P Pfeifer; Jobst Greeve
- Book ID
- 114147584
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 684 KB
- Volume
- 1577
- Category
- Article
- ISSN
- 0167-4781
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