Endothelin-1, big endothelin-1, and nitr
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Ivanka Mikulić; József Petrik; Krešimir Galešić; Željko Romić; Ivana Čepelak; Mo
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Article
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2009
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John Wiley and Sons
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English
⚖ 148 KB
## Abstract The complex pathogenesis of chronic renal disease (CRD) depends on endothelin (ET) axis (ETs and ET receptors) and nitric oxide (NO) because of their vasoactive effects and their role in general modulation of vascular homeostasis. Various renal cells synthesize ETs and NO that play a si