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Reduced endothelin-1- and nitric oxide-mediated arteriolar tone in hypertensive renal transplant recipients

✍ Scribed by Passauer, Jens; Lassig, Grit; Bussemaker, Eckhart; Pistrosch, Frank; Gross, Peter


Book ID
109065425
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
151 KB
Volume
65
Category
Article
ISSN
0085-2538

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## Abstract The complex pathogenesis of chronic renal disease (CRD) depends on endothelin (ET) axis (ETs and ET receptors) and nitric oxide (NO) because of their vasoactive effects and their role in general modulation of vascular homeostasis. Various renal cells synthesize ETs and NO that play a si