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Reduced density of NMDA receptors and increased sensitivity to dizocilpine-induced learning impairment in aged rats

✍ Scribed by Donald K. Ingram; Paolo Garofalo; Edward L. Spangler; Charles R. Mantione; Ikuo Odano; Edythe D. London


Book ID
115803031
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
886 KB
Volume
580
Category
Article
ISSN
0006-8993

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## Abstract Using quantitative receptor autoradiography, we assessed binding site densities and distribution patterns of glutamate, GABA~A~, acetylcholine (ACh), and monoamine receptors in the hippocampus of 32‐month‐old Fischer 344/Brown Norway rats. Prior to autoradiography, the rats were divided