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Reduced decorin affinity for osteogenesis imperfecta collagens

โœ Scribed by K.L. Reigle; L. Sergott; J.L. Lauer_Fields; G.B. Fields; E. Marakeeva; S. Leikin; JC; ; Marini; J.D. San Antonio


Book ID
116729442
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
66 KB
Volume
25
Category
Article
ISSN
0945-053X

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๐Ÿ“œ SIMILAR VOLUMES


Consortium for osteogenesis imperfecta m
โœ Joan C. Marini; Antonella Forlino; Wayne A. Cabral; Aileen M. Barnes; James D. S ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 307 KB

Osteogenesis imperfecta (OI) is a generalized disorder of connective tissue characterized by fragile bones and easy susceptibility to fracture. Most cases of OI are caused by mutations in type I collagen. We have identified and assembled structural mutations in type I collagen genes (COL1A1 and COL1