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Reduced cytotoxic CD8+ lymphocytes in heterozygous UCP2-KO mice in experimental autoimmune encephalomyelitis

✍ Scribed by Lars Manzke; Richard K. Porter


Book ID
113484801
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
57 KB
Volume
1797
Category
Article
ISSN
0005-2728

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## Abstract To analyze immunologic mechanisms involved in experimental autoimmune encephalomyelitis (EAE), a system for studying the cytotoxic reaction of guinea pig lymphocytes against syngeneic macrophages pulsed with myelin basic protein (BP) was developed. It was found that both EAE‐susceptible