✦ LIBER ✦

Reduced chemotaxis of polymorphonuclear leukocytes in sera from patients with rheumatoid arthritis

✍ Scribed by H. Beeuwkes; A. Bijlsma

Publisher: Springer Netherlands
Year: 1974
Tongue: English
Weight: 715 KB
Volume: 40
Category: Article
ISSN: 0003-6072
DOI: 10.1007/bf00394381

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✦ Synopsis

BEEUWKES,/-' I. and BIJLSMA, A. 1974. Reduced chemotaxis of polymorphonuclear leukocytes in sera from patients with rheumatoid arthritis. Antonie van Leeuwenhoek 40: 233-239.

The chemotaxis of normal leukocytes washed and suspended in Hanks solution is inhibited by addition of serum from patients with definite rheumatoid arthritis as was shown by experiments in which an extract from Proteus mirabilis served as attractant. From a suspension of normal leukocytes to which normal serum had been added, significantly more leukocytes actively moved through a millipore filter toward the attractant than from a suspension of similar leukocytes in serum from patients.

1 The chemical and statistical analyses were performed at the Laboratory for Clinical Chemistry. We thank Mr. P. Brombacher for his cooperation.

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