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Reduced 15S-Lipoxygenase-2 Expression in Esophageal Cancer Specimens and Cells and Upregulation In Vitro by the Cyclooxygenase-2 Inhibitor, NS398

โœ Scribed by Xu, Xiao-Chun; Shappell, Scott B.; Liang, Zhengdong; Song, Shumei; Menter, David; Subbarayan, Vemparala; Iyengar, Sunita; Tang, Dean G.; Lippman, Scott M.


Book ID
122246293
Publisher
Neoplasia Press
Year
2003
Tongue
English
Weight
384 KB
Volume
5
Category
Article
ISSN
1522-8002

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โœ Li, Ming (author);Wu, Xiuyuan (author);Xu, Xiao Chun (author) ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 177 KB

Non-steroidal anti-inflammatory drugs (NSAIDs) can induce tumor cells to undergo apoptosis in vitro. They have also shown cancer-preventive activity in vivo. The mechanism of their effects is, however, not well defined. We investigated the mechanism by which a new NSAID, NS398, induces apoptosis in