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Redox regulation of cell signalling

✍ Scribed by Lander, Harry M.; Milbank, Aaron J.; Tauras, James M.; Hajjar, David P.; Hempstead, Barbara L.; Schwartz, Gregory D.; Kraemer, Rosemary T.; Mirza, Urooj A.; Chait, Brian T.; Burk, Sharon Campbell


Book ID
109796005
Publisher
Nature Publishing Group
Year
1996
Tongue
English
Weight
991 KB
Volume
381
Category
Article
ISSN
0028-0836

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## Abstract Extracellular signal‐regulated kinase (Erk)1/2 activity signals myeloid cell differentiation induced by 12‐O‐tetradecanoyl‐phorbol‐13‐acetate (TPA). Previously, we reported that Erk1/2 activation (phosphorylation) induced by TPA required reactive oxygen species (ROS) as a second messeng