Dysregulation of apoptotic signaling in
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Jessica Plati; Octavian Bucur; Roya Khosravi-Far
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Article
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2008
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John Wiley and Sons
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English
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## Abstract Apoptosis is a tightly regulated cell suicide program that plays an essential role in the maintenance of tissue homeostasis by eliminating unnecessary or harmful cells. Defects in this native defense mechanism promote malignant transformation and frequently confer chemoresistance to tra