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Redox reactions of isoalloxazines with 2-hydroxy-1,3-propanedithiol and NADH; the roles of the 4α- and 5-positions.

✍ Scribed by Stewart J. Gumbley; Lyndsay Main

Publisher: Elsevier Science
Year: 1976
Tongue: French
Weight: 214 KB
Volume: 17
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)93882-6

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✦ Synopsis

Kinetic evidence eliminates the 6-and I-positions as essential centres for dithiol addition in reduction of some new isoalloxazines; and suggests that specific orientation effects of NADH within its complexes with the isoalloxazines may be responsible for the abnormal order of relative rates of isoalloxazine reduction observed.

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